Rotrex Supercharging Question on Honda K20a

I am looking at adding a Rotrex supercharger to a K20a Honda engine with an 11.5:1 compression ratio, since, well, it's what I have right now, and until something breaks, I'd like to avoid tearing it down to lower the compression ratio. All my reading to this point suggests that the compression is creeping a little high for a forced induction application, but much of the conventional forum "wisdom" seems based on older fuels prior to the prevalence of e85 availability. So, to anyone with experience, is utilizing e85 enough of a safeguard to allow some control over detonation around this level of compression, or are there other concerns I should look after as well? I believe I can get enough cooling with an air-to-air setup, and I've done some loose calculations to ensure my fuel pump and injectors can handle the increased load. Not sure if additional control like methanol injection is advised, but I was hoping to avoid any additional complexities if I can. Any input is appreciated, thanks!

You don't mention the boost you are considering?

You 'should' be OK for low boost levels - I'd suggest starting low and monitoring for signs of detonation or other issues as you increase the boost level.

I'd also suggest picking up one of the test kits and monitoring exactly what the E percentage actually is - it can legally vary by a fair bit, and if you have a high E tune and the bowser has a low E percentage...

Good point since there are multiple blower options. I am looking at the Rotrex C30-94, which I think will be somewhere in the 12-14psi range at peak. Wanted to start a little more conservatively than jumping up to a bigger C38 series.

And a test kit will definitely be in my future! Was also considering whether to go with a race gas e85 depending on how pump e85 looks here. I'm fairly far north, so I'm guessing winter blending will have some impact on the quality of pump gas available.