Staged injection - Angle/placement of injectors - does it matter?

Hey guys,

Setting up the second rail on a customer's Evo - looking to run the long pintle Bosch 0280158040's in an aftermarket Evo intake manifold.

With regards to welding in the injector bosses and mounting the rail, does the injector placement really matter? Because at the end of the day, the second set of injectors will be kicking in after 20psi+, fuel would be fuel at that point?

If someone can point me in the right direction, that would be greatly appreciated!